Specialist Testing · Environmental Toxin Burden
EnviroTOX Complete
Environmental Toxin Panel
Mycotoxins, glyphosate, and over 170 environmental chemicals — measured in a single urine collection. The most comprehensive environmental toxin panel available in UK private practice, for when the question is what the body is carrying that conventional medicine isn't looking for.
What EnviroTOX Complete Is
EnviroTOX Complete is a three-panel environmental toxin assessment run from a single first-morning urine sample. It combines the MycoTOX mycotoxin profile, the ToxDetect environmental chemical panel, and a dedicated glyphosate and AMPA measurement — three investigations that address different categories of environmental chemical exposure, delivered as one integrated report.
The clinical rationale is straightforward: environmental toxin exposures rarely occur in isolation. A client living in an older property with damp issues who eats a conventional UK diet and lives near agricultural land is likely carrying mycotoxin burden, glyphosate metabolites, and a range of industrial chemical residues simultaneously. Testing for one category in isolation misses the total environmental load — and total load is what matters clinically, because the combined effect of multiple sub-threshold exposures is not additive but synergistic.
EnviroTOX Complete is the right test when the environmental picture is broad or unclear. When the clinical suspicion is specifically and narrowly mould exposure, MycoTOX alone at £398 is the appropriate and more cost-effective choice. When the picture includes agricultural chemical exposure, industrial chemical history, unexplained endocrine disruption, or a general question about total environmental burden — EnviroTOX Complete answers a broader question.
11 toxins
11 mycotoxins from 40+ mould species including Aflatoxins, Ochratoxin A, Trichothecenes (black mould), Zearalenone, Fumonisins, Gliotoxin, and Mycophenolic acid. Mass spectrometry detection.
170+ chemicals
Phthalates, parabens, benzene derivatives, styrene, xylene, organophosphate pesticides, polycyclic aromatic hydrocarbons, MTBE, acrylamide, and industrial solvents. The most comprehensive environmental chemical screen available.
2 markers
Glyphosate (the active herbicide in Roundup and hundreds of other products) and AMPA (aminomethylphosphonic acid — the primary glyphosate metabolite). Together these confirm actual glyphosate body burden from dietary and environmental exposure.
The Glyphosate Question
Glyphosate is the most widely used herbicide in the world and the most heavily used agricultural chemical in UK food production. It is applied to wheat, oats, barley, and other cereal crops as a pre-harvest desiccant — meaning it is sprayed directly onto the crop shortly before harvest to accelerate drying and standardise the harvest date. This is not a trace agricultural residue from spraying during the growing season. It is deliberate, high-volume application to the food crop immediately before it enters the food supply.
Glyphosate residues are routinely detected in UK cereals, bread, oats, and processed foods at levels that regularly exceed what regulatory bodies consider acceptable — and the regulatory framework for what is acceptable is itself contested, with a growing body of independent research suggesting that current permitted levels are not safe for chronic, cumulative, daily exposure across a lifetime.
The glyphosate mechanism — what it does in the body
Why glyphosate is more than a herbicide residue
Shikimate pathway disruption
Glyphosate was designed to inhibit the shikimate pathway — an enzyme pathway in plants that humans don't have. The problem is that gut bacteria do have it. Glyphosate selectively kills or suppresses beneficial gut bacteria that use this pathway, disrupting the microbiome in ways that favour opportunistic organisms.
Aromatic amino acid depletion
The shikimate pathway in gut bacteria produces aromatic amino acids — tryptophan, tyrosine, and phenylalanine — which are the direct precursors of serotonin, dopamine, and noradrenaline. Glyphosate-mediated disruption of this pathway reduces the microbial contribution to neurotransmitter precursor availability.
Mineral chelation
Glyphosate is a potent chelator of divalent cations — it binds manganese, zinc, cobalt, iron, and copper. Chronic exposure depletes these minerals from soil (reducing nutritional content of food) and potentially from the body. Manganese is a cofactor for numerous enzyme systems including superoxide dismutase.
Cytochrome P450 inhibition
Glyphosate inhibits cytochrome P450 enzymes — the liver's primary detoxification machinery. Impaired CYP450 function reduces the ability to metabolise hormones, clear toxins, and process medications. This may explain why glyphosate-exposed individuals show greater sensitivity to other chemical exposures.
Intestinal permeability
Glyphosate disrupts tight junction proteins in the intestinal epithelium — the proteins that maintain the selective barrier between the gut lumen and the bloodstream. This mechanism is directly relevant to the intestinal permeability picture seen in many chronic gut presentations, particularly those that don't fully resolve with standard gut protocols.
Endocrine disruption
Glyphosate has documented endocrine-disrupting effects at concentrations below current regulatory limits. Effects include oestrogen receptor agonism, thyroid hormone disruption, and interference with gonadal steroidogenesis. The mechanism overlaps with Zearalenone — the mycotoxin with oestrogenic activity — creating compounding endocrine disruption when both are present.
The folic acid fortification connection
Glyphosate's disruption of the shikimate pathway in gut bacteria reduces microbial tryptophan and folate production. This is clinically relevant to the folic acid fortification debate — mandatory synthetic folic acid addition to flour addresses one aspect of folate status while leaving the microbial production pathway disrupted by the glyphosate applied to that same flour's grain source. Measuring glyphosate body burden in clients with MTHFR variants, depression, anxiety, or folate metabolism concerns adds a mechanistic layer that the standard clinical picture misses entirely.
The ToxDetect Panel — Environmental Chemicals
The ToxDetect panel screens for over 170 environmental chemicals across multiple classes — the compounds that accumulate in human tissue through everyday exposure to food packaging, personal care products, household chemicals, polluted air, and industrial environments. These are not exotic toxins requiring unusual exposure — they are ubiquitous in the modern environment and detectable in the urine of the vast majority of the population tested.
| Chemical class |
Key compounds measured |
Primary exposure routes |
Documented health effects |
| Phthalates |
DEHP, DBP, BBP, DINP metabolites |
Plastic food packaging, PVC flooring, personal care products, medical devices |
Endocrine disruptor
Anti-androgenic
Developmental
|
| Parabens |
Methylparaben, ethylparaben, propylparaben, butylparaben |
Cosmetics, skin care, shampoo, food preservatives |
Oestrogenic
Allergenic
|
| Benzene derivatives |
Benzene, toluene, styrene, xylene (BTSX) |
Petrol, paint, adhesives, cleaning products, urban air pollution, off-gassing from furnishings |
Neurotoxic
Immunotoxic
Carcinogenic (benzene)
|
| Organophosphate pesticides |
Chlorpyrifos metabolites, malathion metabolites, DEET metabolites |
Agricultural food residues, domestic pest control, some personal insect repellents |
Neurotoxic
Endocrine disruptor
Metabolic disruption
|
| Polycyclic aromatic hydrocarbons |
Naphthalene, fluorene, phenanthrene metabolites |
Grilled and smoked foods, urban air, tobacco smoke, vehicle exhaust |
Carcinogenic
Endocrine disruptor
Immunotoxic
|
| Acrylamide |
Acrylamide, glycidamide |
High-temperature processed starchy foods (chips, crisps, toast, biscuits, coffee) |
Neurotoxic
Probable carcinogen (Group 2A)
|
| MTBE / Fuel additives |
MTBE, ETBE |
Petrol contamination of groundwater, urban air, petrol station exposure |
Neurotoxic
Possible carcinogen
|
| Phthalate alternatives |
DINCH, DEHA metabolites |
Food packaging, medical plastics (increasingly replacing traditional phthalates) |
Emerging data — endocrine concern
|
A note on cumulative exposure
Each of the chemical classes above has a regulatory exposure limit set individually — an acceptable daily intake calculated in isolation. What the regulatory framework does not account for is cumulative and combined exposure: a person eating conventionally produced food, using standard personal care products, living in an urban environment, and working in an office with synthetic furnishings is simultaneously exposed to phthalates, parabens, benzene derivatives, PAHs, glyphosate, mycotoxins, and acrylamide every single day. The total body burden is what EnviroTOX measures. Individual exposures may be below individual limits — but that is not the same as saying the total load is safe or clinically insignificant.
Who This Test Is For
🌾
Dietary Glyphosate Exposure Concern
Anyone eating conventional (non-organic) UK cereals, bread, oats, or processed grain products is consuming glyphosate residues — this is not a risk, it is a documented fact. EnviroTOX quantifies the actual body burden for clients who want to understand their glyphosate exposure level and the clinical implications, particularly those with gut dysbiosis, intestinal permeability, MTHFR variants, or endocrine disruption that hasn't resolved with standard interventions.
🏭
Industrial or Occupational Exposure History
Clients with occupational exposure to solvents, pesticides, petrochemicals, or industrial environments — or who live near industrial sites, agricultural land, busy roads, or airports. The ToxDetect panel identifies which specific chemical classes are elevated, allowing targeted detoxification and source reduction strategies rather than generic advice.
⚖️
Unexplained Endocrine Disruption
When the DUTCH Plus reveals oestrogen dominance, HPG axis disruption, or androgen imbalance that doesn't have a clear endogenous explanation — environmental oestrogenic chemical exposure is a significant and frequently unmeasured contributor. Phthalates, parabens, glyphosate, and Zearalenone (mycotoxin) all have oestrogenic activity. EnviroTOX identifies whether environmental oestrogen load is part of the clinical picture.
🧠
Neurological Symptoms Without Clear Cause
Cognitive decline, mood disruption, peripheral neuropathy, or neurological symptoms that haven't responded to standard nutritional intervention. Benzene derivatives, organophosphates, and mycotoxins are all neurotoxic. Glyphosate's disruption of neurotransmitter precursor production adds a further mechanism. EnviroTOX provides the full environmental neurological exposure picture.
🔄
Gut Protocols That Keep Failing
Clients who have done multiple rounds of gut treatment — antimicrobials, probiotics, dietary intervention — with limited lasting effect. Glyphosate's ongoing disruption of the gut microbiome, intestinal tight junctions, and CYP450 detoxification creates a revolving door where the gut can't maintain a healthy state because the environmental driver continues. Identifying and addressing environmental load is often what allows gut protocols to finally hold.
🌿
Wanting a Complete Environmental Baseline
For health-aware individuals who want to understand their total environmental toxin burden as a baseline — not because of specific symptoms but because they understand that what the body is carrying accumulates over time and shapes long-term health trajectory. EnviroTOX Complete provides that baseline in one test, with follow-up testing available to track the impact of dietary and lifestyle changes on measured toxin levels.
How EnviroTOX Fits the TDG Investigation
EnviroTOX Complete sits at the intersection of several areas of the TDG framework — its findings are clinically relevant to the gut investigation, the hormone investigation, the neurological picture, and the nutritional status picture simultaneously. This is what makes it both a powerful standalone test and a high-value addition when existing test results raise environmental questions.
EnviroTOX connections across the TDG test suite
GI-MAP Stool Test
Glyphosate disrupts the microbiome via the shikimate pathway — gut dysbiosis that doesn't resolve may have glyphosate as a persistent driver. Mycotoxins cause intestinal permeability that compounds what the GI-MAP identifies. Environmental chemical context explains why gut protocols lose their effect.
DUTCH Plus Hormone Test
Phthalates, parabens, glyphosate, and Zearalenone are all oestrogenic or endocrine-disrupting. When the DUTCH shows oestrogen dominance or HPG axis disruption, EnviroTOX quantifies the environmental oestrogen load contributing to that picture. CYP450 inhibition by glyphosate also affects hormone metabolism directly.
Metabolomix+ OAT
Glyphosate depletes the aromatic amino acid precursors of serotonin and dopamine through gut bacteria shikimate pathway disruption — this shows on the Metabolomix+ amino acid panel. Mycotoxins elevate OAT oxidative stress markers and specific organic acid patterns. EnviroTOX gives the upstream environmental explanation for what the OAT reveals downstream.
Randox Blood Chemistry
Glyphosate chelates manganese, zinc, and copper — the mineral depletion picture on Randox blood chemistry may have environmental chelation as a driver. Liver enzyme elevation on Randox (ALP, ALT, GGT) with environmental toxin burden warrants EnviroTOX to identify whether chemical load is contributing to hepatic stress.
IgG Food Sensitivity (Food MAP)
Glyphosate-mediated intestinal permeability is a direct driver of IgG food sensitisation — the leaky gut that allows food antigens to cross into systemic circulation and generate IgG memory reactions. Removing glyphosate exposure alongside addressing food sensitivities is more likely to produce lasting reduction in IgG reactions than food avoidance alone.
MycoTOX Profile
EnviroTOX Complete includes the full MycoTOX panel. If mould exposure is the primary clinical suspicion, MycoTOX alone at £398 is the more cost-effective choice. EnviroTOX is the choice when mould is one element of a broader environmental picture — or when the source of the clinical picture is unclear and a comprehensive screen is warranted.
MycoTOX Alone vs EnviroTOX Complete
| Feature |
MycoTOX alone |
EnviroTOX Complete |
| Mycotoxin panel (11 toxins) |
✓ Full panel |
✓ Full panel included |
| Glyphosate and AMPA |
✗ |
✓ |
| ToxDetect 170+ environmental chemicals |
✗ |
✓ |
| Phthalates, parabens, benzene derivatives |
✗ |
✓ |
| Organophosphate pesticide metabolites |
✗ |
✓ |
| Acrylamide and PAH metabolites |
✗ |
✓ |
| Sample collection |
First-morning urine |
First-morning urine (same collection) |
| Client fee |
£398 |
£819 |
| Best when |
Mould is the primary and specific clinical suspicion |
Environmental picture is broad, unclear, or multi-source |
The Process
1
Consultation — environmental history and clinical context
We discuss your symptom history, dietary patterns, living and working environment, occupational history, and any previous test results. This determines whether EnviroTOX Complete or MycoTOX alone is the appropriate test, and provides the context needed to interpret results meaningfully when they return.
2
Test kit and creatine loading preparation
The EnviroTOX Complete kit is sent to your home. As with MycoTOX, creatine loading in the days before collection improves sensitivity for the mycotoxin panel by mobilising toxins from tissue stores. Detailed preparation instructions are included. The ToxDetect and glyphosate elements do not require specific preparation beyond the standard fasting requirements.
3
First-morning urine collection
Single collection, prepaid return envelope to the Mosaic laboratory. All three panels — MycoTOX, ToxDetect, and glyphosate — are run from the same sample. Turnaround is typically 10–14 days from receipt at the laboratory.
4
Integrated three-panel results interpretation
The report is reviewed across all three panels together — because the clinical significance of individual findings often depends on what else is elevated. High glyphosate alongside mycotoxins and phthalates represents a different clinical picture from isolated glyphosate elevation alone. The interpretation consultation addresses each elevated category, the likely sources, and the priority sequencing for intervention.
5
Protocol — source reduction, drainage, and detoxification support
The protocol addresses three things in sequence: source reduction (dietary changes, environmental assessment recommendations, product swaps), drainage support (liver, kidneys, lymphatics — the excretion pathways that need to be open before mobilising toxins), and active detoxification support (binders, glutathione repletion, specific nutrient cofactors for CYP450 function). The sequence matters — mobilising toxins without adequate drainage and excretion capacity worsens the symptom picture before it improves.
Pricing
EnviroTOX Complete — Mosaic Diagnostics via Nordic Laboratories
EnviroTOX Complete (MycoTOX + ToxDetect + Glyphosate)
£819
MycoTOX alone (if mould is the primary suspicion)
£398
Saving with EnviroTOX vs panels ordered separately
Bundled pricing — confirm individual panel costs at consultation
Results interpretation consultation
£145
The complexity of an EnviroTOX Complete interpretation — three panels across 170+ markers — typically warrants a longer consultation than a single-panel result. This will be discussed at booking. Prices correct at July 2026 — confirm current pricing when ordering.
Reducing exposure — practical starting points
Regardless of test results, the single highest-impact dietary change for reducing glyphosate body burden is switching wheat, oats, and other cereal products to certified organic. UK organic certification prohibits glyphosate pre-harvest desiccation — the primary route of high-level cereal contamination. For broader environmental chemical reduction: glass or stainless steel food storage instead of plastic, fragrance-free personal care products, and increased dietary diversity with emphasis on organic produce are the three changes with the most evidence for measurable reduction in urinary chemical metabolites within 4–6 weeks.
What is your environmental toxin burden?
Book an initial consultation to discuss your dietary history, environmental exposures, and current clinical picture. We'll determine whether EnviroTOX Complete, MycoTOX alone, or a different investigation is the right starting point — and what the results mean for your specific health goals.
Book a Consultation
MycoTOX — Mould Focus Only